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当前位置： 首页 > 产品中心 > peptide > BD Biosciences/APC Mouse Anti-Human IL-2/5 μL/341116
商品详细BD Biosciences/APC Mouse Anti-Human IL-2/5 μL/341116
BD Biosciences/APC Mouse Anti-Human IL-2/5 μL/341116
BD Biosciences/APC Mouse Anti-Human IL-2/5 μL/341116
商品编号： 341116
品牌： bdbiosciences
市场价： ¥11548.53
美元价： 6599.16
产地： 美国(厂家直采)
公司：
产品分类： 多肽合成
公司分类： peptide
联系Q Q： 3392242852
电话号码： 4000-520-616
电子邮箱： info@ebiomall.com
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商品介绍
Product DetailsRecommended AssayReferences

Description

Anti-Hu–IL-2, clone 5344.111, is derived from a fusion of Sp2/0 myeloma cells with splenocytes from BALB/c mice immunized with recombinant human IL-2.

Anti-Human Interleukin-2 (Anti-Hu–IL-2) recognizes a 15- to 18-kilodalton (kd) glycoprotein.

Format
  • FormatAPC
  • Excitation SourceRed 633 nm
  • Excitation Max650nm
  • Emission Max660nm

Allophycocyanin (APC), is an accessory photosynthetic pigment found in blue-green algae. Its molecular weight is approximately 105 kDa. APC has six phycocyanobilin chromophores per molecule, which makes it a very bright fluorochrome that is highly suitable for flow cytometry applications. Due to nearly identical excitation and emission properties but different spillover characteristics, APC and Alexa Fluor® 647 cannot be used simultaneously

Other Formats→

  • FITC
  • PE
      Resources & Tools
      Spectrum ViewerPanel DesignerSpectrumViewerDownload MSDSDownload TDS
      Preparation and Storage

      The FITC conjugate is supplied as 12.5 µg in 1.0 mL (12.5 µg/mL) of PBS. The PE conjugate is supplied as 1.6 µg in 1.0 mL (1.6 µg/mL) of PBS. The APC conjugate is supplied as 3 µg in 0.5 mL (6 µg/mL) of PBS. PBS contains gelatin and 0.1% sodium azide.

      Store vials at 2°C–8°C. Conjugated forms should not be frozen. Protect from exposure to light. Each reagent is stable until the expiration date shown on the bottle label when stored as directed.

      1. Aggarwal BB, Puri RK. Common and uncommon features of cytokines and cytokine receptors: an overview. In: Human Cytokines: Their Role in Disease and Therapy. Cambridge, MA: Blackwell Science; 1995:3-24.

      2. Clerici M, Hakim FT, Venzon DJ, et al. Changes in interleukin-2 and interleukin-4 production in asymptomatic, human immunodeficiency virus-seropositive individuals. J Clin Invest. 1993;91:759-765.

      3. Clerici M, Shearer GM. A TH1 → TH2 switch is a critical step in the etiology of HIV infection. Today. 1993;14:107-110.

      4. Cook EB, Stahl JL, Lowe L, et al. Simultaneous measurement of six cytokines in a single sample of human tears using microparticle-based flow cytometry: allergics vs non-allergics. J Immmol Meth. 2001;254:109-118.

      5. Croft M, Carter L, Swain S, Dutton RW. Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting Type 2 versus Type 1 cytokine profiles. J Exp Med. 1994;180:1715-1728.

      6. ElGhazali GEB, Paulie S, Andersson G, et al. Number of interleukin-4– and interferon- γ –secreting human T cells reactive with tetanus toxoid and the mycobacterial antigen PPD or phytohemagglutinin: distinct response profiles depending on the type of antigen used for activation. Eur J Immunol. 1993;23:2740-2745.

      7. Elson LH, Nutman TB, Metcalfe DD, Prussin C. Flow cytometric analysis for cytokine production identifies T helper 1, T helper 2, and T helper 0 cells within the human CD4+ CD27- lymphocyte subpopulation. J Immunol. 1995;154:4294-4301

      8. Graves JD, Downward J, Izquierdo-Pastor M, Rayter S, Warne PH, Cantrell DA. The growth factor IL-2 activates p21ras proteins in normal human lymphocytes. J Immunol. 1992;148:2417-2422.

      9. Graziosi C, Pantaleo G, Gantt KR, et al. Lack of evidence for the dichotomy of T H 1 and T H 2 predominance in HIV-infected individuals. Science. 1994;265:248-252.

      10. Gusella GL, Musso T, Bosco MC, Expinoza-Delgado I, Matsushima K, Varesio L. IL-2 upregulates but IFN-γ suppresses IL-8 expression in human monocytes. J Immunol. 1993;151:2725-2732.

      11. Hillman GG, Haas GP. Role of cytokines in lymphocyte functions. Human Cytokines: Their Role in Disease and Therapy. 1995:37-54.

      12. Hyjek E, Lischner HW, Hyslop T, et al. Cytokine patterns during progression to AIDS in children with perinatal HIV infection. J Immunol. 1995;155:4060-4071.

      13. Lanier LL, Benike CJ, Phillips JH, Engleman EG. Recombinant interleukin-2 enhanced natural killer cell– mediated cytotoxicity in human lymphocyte subpopulations expressing the Leu-7 and Leu-11 antigens. J Immunol. 1985;134:794-801.

      14. Maggi EM, M, Ravina A, Annunziato F, et al. Ability of HIV to promote a T H 1 to T H 0 shift and to replicate preferentially in TH2 and TH0 cells. Science. 1994;265:244-248.

      15. Musso T, Espinoza-Dalgado I, Pullki K, Gusella G, Longo D, Varesio L. IL-2 induces IL-6 production in human monocytes. J Immunol. 1992;148:795-800.

      16. Openshaw P, Murphy EE, Hosken NA, et al. Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations. J Exp Med. 1995;182:1357-1367.

      17. Phillips JH, Gemlo BT, Myers WW, Rayner AA, Lanier LL. In vivo and in vitro activation of natural killer cells in advanced cancer patients undergoing combined recombinant interleukin-2 and LAK cell therapy. J Clin Oncology. 1987;5:1933-1941.

      18. Picker LJ, Singh MK, Zdraveski Z, et al. Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometry. Blood. 1995;86:1408-1419.

      19. Röcken M, Müller KM, Saurat J-H, et al. Central role for TCR/CD3 ligation in the differentiation of CD4+ T cells toward a TH1 or TH2 functional phenotype. J Immunol. 1992;148:1031-1036.

      20. Röcken M, Saurat J-H, Hauser C. A common precursor for CD4+ T cells producing IL-2 or IL-4. J Immunol. 1992;148:47-54.

      21. Street NE, Mosmann TR. Functional diversity of T lymphocytes due to secretion of different cytokine patterns. FASEB J. 1991;5:171-176.

      22. Suni MA, Picker LJ, Maino VC. Detection of antigen-specific T cell cytokine expression in whole blood by flow cytometry. J Immunol Methods. 1998;212:89-98.

      23. Zhang X, Giangreco L, Broome E, Dargan CM, Swain SL. Control of CD4 effector fate: transforming growth factor β 1 and interleukin-2 synergize to prevent apoptosis and promote effector expansion. J Exp Med. 1995;182:669-709.

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      BD是世界上最大的生产和销售医疗设备、医疗系统和试剂的医疗技术公司之一。致力于提高全世界人类的健康水平。BD专注于改进药物治疗，提高传染性疾病诊断的质量和速度，推进新型药物和疫苗的研究与发现。BD公司具有强大的研发能力和世界上最棘手的多种疾病进行斗争的能力。公司于1897年在纽约成立，总部位于美国新泽西州的富兰克林湖，业务遍及全球。公司的业务可分为BD医疗、BD诊断、BD生物科学三大类，生产销售包括医用耗材、实验室仪器、抗体、试剂、诊断等产品。公司的服务对象包括医疗机构，生命科学研究所，临床实验室，工业单位和普通大众。BD has state-of-the-art facilities around the globe that provide an environment that enables our highly talented workforce to be the best at their professions. We hire associates who have a passion and commitment to advancing the world of health. We are always seeking great people to join our company on its journey to greatness.BDRat Granulocytes Pure RP-1  500ug550002BDMs Ig Kpa Lgt Chain FITC 187.1  500ug550007BDICC Fixation Buffer 100mL550011BDMs CD210 NALE 1B1.3a 500ug550019BDMs CD51 Pure RMV-7 100ug550026BDMs CD5 APC 53-7.3 100ug550037BDHu CD62E PE-Cy5 68-5H11 100Tst550041BDHu CD95 Pure EOS9.1  100ug550052BDHam IgG2 Kpa ItCl FITC B81-3 250ug550057BDMs Crry/p65 Pure 1F2 100ug550059BDMs IL-4 Recom Protein 10ug550068BDMs IL-2 Recom Protein 20ug550070BDHu IL-6 Recom Protein 10ug550072BDHu MIP-1 Bta PE D21-1351 100ug550082BDMs IgG1 PE A85-1 100ug550084BDHam IgG2 Kpa ItCl PE B81-3 100ug550086BDHu CD142 Pure HTF-1 100ug550254BDHu CD1d PE CD1d42 100Tst550256BDHu CD73 PE AD2 100Tst550258BDHu CD103 FITC Ber-ACT8 100Tst550260BDMs CD11c APC HL3 100ug550268BDMs CD72b/c Aloatg PE JY/93 100ug550270BDRat CD32 Pure D34-485 500ug550272BDRat CD32 NALE D34-485 500ug550274BDMs CD3e IHC Pure 145-2C11 1mL550277BDMs CD4 IHC Pure H129.19 1mL550280BDMs CD8a IHC Pure 53-6.7 1mL
      公司介绍
      BD是世界上最大的生产和销售医疗设备、医疗系统和试剂的医疗技术公司之一。致力于提高全世界人类的健康水平。BD专注于改进药物治疗，提高传染性疾病诊断的质量和速度，推进新型药物和疫苗的研究与发现。BD公司具有强大的研发能力和世界上最棘手的多种疾病进行斗争的能力。公司于1897年在纽约成立，总部位于美国新泽西州的富兰克林湖，业务遍及全球。公司的业务可分为BD医疗、BD诊断、BD生物科学三大类，生产销售包
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