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当前位置： 首页 > 产品中心 > peptide > BD Biosciences/Purified Mouse Anti-Human CD57/20 μL/347390
商品详细BD Biosciences/Purified Mouse Anti-Human CD57/20 μL/347390
BD Biosciences/Purified Mouse Anti-Human CD57/20 μL/347390
BD Biosciences/Purified Mouse Anti-Human CD57/20 μL/347390
商品编号： 347390
品牌： bdbiosciences
市场价： ¥6005.16
美元价： 3431.52
产地： 美国(厂家直采)
公司：
产品分类： 多肽合成
公司分类： peptide
联系Q Q： 3392242852
电话号码： 4000-520-616
电子邮箱： info@ebiomall.com
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商品介绍
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Description

CD57, clone HNK-1, is derived from hybridization of mouse P3-X63-Ag8.653 myeloma cells with lymph node cells from BALB/c mice immunized with membrane extracts of the HSB-2 T–lymphoblastoid cell line.

CD57 (Leu-7) recognizes an Mr 110-kdalton (kDa) glycoprotein that is expressed on a subset of natural killer (NK) lymphocytes and T lymphocytes. The antigen is a carbohydrate structure associated with myelin-associated glycoprotein (MAG).

Format
  • FormatPurified

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  • FITC
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        Preparation and Storage

        The monoclonal antibody is supplied as 25 µg purified immunoglobulin in 2.0 mL (12.5 µg/mL) of phosphate-buffered saline. The FITC conjugate is supplied as 25 µg in 2.0 mL (12.5 µg/mL). The biotin conjugate is supplied as 25 µg in 2.0 mL (12.5 µg/mL). Buffered saline contains gelatin and 0.1% sodium azide. The vials should be stored at 2° to 8°C. Conjugated forms should not be frozen and should be protected from prolonged exposure to light. Each reagent is stable for the period shown on the bottle label when stored as directed.

        1. Abo T, Balch CMA. A differentiation antigen of human NK and K cells identified by a monoclonal antibody (HNK-1). J Immunol. 1981;127:1024-1029.

        2. Bunn PA, Gazdar AF, Carney DN, Minna J. Small cell lung carcinoma and natural killer cells share an antigenic determinant, Leu-7. Clin Res. 1984;32:416A

        3. Kruse J, Mailhammer R, Wennecke H, et al. Neural cell-adhesion molecules and MAG share a common carbohydrate moiety recognized by monoclonal antibodies L2 and HNK-1. Nature. 1984;311:153-155.

        4. Lanier LL, Le AM, Civin C, Loken MR, Phillips JH. The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes. J Immunol. 1986;136(4):4480-4486.

        5. Lanier LL, Le AM, Phillips JH, Warner NL, Babcock GF. Subpopulations of human natural killer cells defined by expression of the Leu-7 (HNK-1) and Leu-11 (NK-15) antigens. J Immunol. 1983;131:1789-1796.

        6. Lewis DE, Puck JM, Babcock GM, Rich RR. Disproportionate expansion of a minor T cell subset in patients with lymphadenopathy syndrome and acquired immunodeficiency syndrome. J Infect Disease. 1985;151:555.

        7. Manara GC, De Panfilis G, Ferrari C. Ultrastructural characterization of human large granular lymphocyte subsets defined by the expression of HNK-1 (Leu-7), Leu-11, or both HNK-1 and Leu-11 antigens. J Histochem Cytochem. 1985;33:1129-1133.

        8. McGarry RC, Helfand SL, Quarles RH, Roder JC. Recognition of myelin-associated glycoprotein by the monoclonal antibody HNK-1. Nature. 1983;306:376

        9. Mechtersheimer G, Staudter M, Moller P. Expression of the natural killer cell-associated antigens CD56 and CD57 in human neural and striated muscle cells and in their tumors. Cancer Res. 1991;51:1300-1307.

        10. Prince HE, Kreiss JK, Kasper CK, et al. Distinctive lymphocyte subpopulation abnormalities in patients with congenital coagulation disorders who exhibit lymph node enlargement. Blood. 1985;66:64.

        11. Schubert J, Lanier LL, Schmidt RE. Cluster report: CD57. In: Knapp W, Dörken B, Gilks WR, et al, eds. Leucocyte Typing IV: White Cell Differentiation Antigens. New York, NY; Oxford University Press; 1989:711-714.

        12. Stites D, Casavant C, McHugh T, et al. Flow cytometric analysis of lymphocyte phenotypes in AIDS using monoclonal antibodies and simultaneous dual immunofluorescence. Clin Immunol Immunopathol. 1986;38:161-177.

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        BD是世界上最大的生产和销售医疗设备、医疗系统和试剂的医疗技术公司之一。致力于提高全世界人类的健康水平。BD专注于改进药物治疗，提高传染性疾病诊断的质量和速度，推进新型药物和疫苗的研究与发现。BD公司具有强大的研发能力和世界上最棘手的多种疾病进行斗争的能力。公司于1897年在纽约成立，总部位于美国新泽西州的富兰克林湖，业务遍及全球。公司的业务可分为BD医疗、BD诊断、BD生物科学三大类，生产销售包
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