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当前位置: 首页 > 产品中心 > peptide > BD Biosciences/Anti-Human CD8 FITC/CD38 PE/20 µL/349527
商品详细BD Biosciences/Anti-Human CD8 FITC/CD38 PE/20 µL/349527
BD Biosciences/Anti-Human CD8 FITC/CD38 PE/20 µL/349527
BD Biosciences/Anti-Human CD8 FITC/CD38 PE/20 µL/349527
商品编号: 349527
品牌: bdbiosciences
市场价: ¥9946.44
美元价: 5683.68
产地: 美国(厂家直采)
公司:
产品分类: 多肽合成
公司分类: peptide
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Product DetailsRecommended AssayReferences

Description

The CD8 antibody, clone SK1, is derived from hybridization of NS-1 mouse myeloma cells with spleen cells from BALB/c mice immunized with human peripheral blood T lymphocytes.

The CD38 antibody, clone HB-7, is derived from hybridization of P3-X63-Ag8.653 mouse myeloma cells with spleen cells from BALB/c mice immunized with the BJAB cell line.

The CD8 (Leu-2a) antigen is present on the human suppressor/cytotoxic T-lymphocyte subset as well as on a subset of natural killer (NK) lymphocytes. The CD8 antigenic determinant interacts with class I major histocompatibility complex (MHC) molecules resulting in increased adhesion between the CD8+ T lymphocytes and the target cells. Binding of the CD8 antigen to class I MHC molecules enhances the activation of resting T lymphocytes. CD8 recognizes an antigen expressed on the 32-kdalton (kDa) α-subunit of a disulfide-linked bimolecular complex. The cytoplasmic domain of the α-subunit of the CD8 antigen is associated with the protein tyrosine kinase p56lck.

CD38 (Leu-17) recognizes an antigen that is an integral membrane glycoprotein, Mr 45 kDa, with a protein core of 35 kDa.

Contents

SpecificityCloneFormatIsotypeEntrez Gene ID
CD8SK1FITCIgG1, κ925
CD38HB7 (also known as HB-7)PEIgG1, κ952
Preparation and Storage

Store vials at 2°C–8°C. Conjugated forms should not be frozen. Protect from exposure to light. Each reagent is stable until the expiration date shown on the bottle label when stored as directed.

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