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当前位置: 首页 > 产品中心 > peptide > BD Biosciences/Anti-Human CD2/CD2R Purified/340366
商品详细BD Biosciences/Anti-Human CD2/CD2R Purified/340366
BD Biosciences/Anti-Human CD2/CD2R Purified/340366
BD Biosciences/Anti-Human CD2/CD2R Purified/340366
商品编号: 340366
品牌: bdbiosciences
市场价: ¥0.00
美元价: 0.00
产地: 美国(厂家直采)
公司:
产品分类: 多肽合成
公司分类: peptide
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Product DetailsRecommended AssayReferences

Description

CD2, clone L303.1, and CD2R, clone L304.1, are each derived by the fusion of SP2/0 myeloma cells with splenocytes from BALB/c mice immunized with CD3-activated human T lymphocytes.

The CD2 molecule is an Mr 50-kilodalton (kd) human lymphocyte antigen. At least three different functional epitopes of CD2 have been defined. One epitope (recognized by Leu™-5b) is the sheep red blood cell (SRBC) receptor. The other two epitopes, CD2 and CD2R, are binding sites for monoclonal antibodies that, when used together, deliver signals for polyclonal T-lymphocyte activation.

Contents

SpecificityCloneFormatIsotypeEntrez Gene ID
CD2L303.1 (also known as L303)PurifiedIgG2a, κ
CD2RL304.1PurifiedIgG1, κ914
Preparation and Storage

The monoclonal antibody is supplied as 125 μg each of CD2 and CD2R in 250 μL of phosphate-buffered saline (PBS) containing 0.01% sodium azide. The vial should be stored at 2° to 8°C. Each reagent is stable for the period shown on the bottle label when stored as directed.

  1. Huet S, Wakasugi H, Sterkers G, et al. T cell activation via CD2 (T, gp50): The role of accessory cells in activating resting T cells via CD2. J Immunol. 1986;137:1420-1428.

  2. Lanier LL, Phillips JH, Hackett J Jr, Tutt M, Kumar V. Natural killer cells: Definition of a cell type rather than a function. J Immunol. 1986;137:2735.

  3. Maino VC, Suni MA, Ruitenberg JJ. Rapid flow cytometric method for measuring lymphocyte subset activation. Cytometry. 1995;20:127-133.

  4. Meuer SC, Hussey RE, Fabbi M, et al. An alternative pathway of T cell activation: A functional role for the 50 kD T11 sheep erythrocyte receptor protein. Cell. 1984;36:897.

  5. Meuer SC. Cluster report: CD2. In: Knapp W, Dörken B, Gilks WR, et al, eds. Leucocyte Typing IV: White Cell Differentiation Antigens. New York, NY: Oxford University Press; 1989:270-272.

  6. Parish CR, McPhun V, Warren HS. Is a natural ligand of the T lymphocyte CD2 molecule a sulfated carbohydrate? J Immunol. 1988;141:3498-3504.

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